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Bicarbonate, Serum

Bicarbonate, Serum

Bicarbonate, serum test measures the level of bicarbonate in the blood to determine electrolyte or acid-base (pH) imbalance. Bicarbonate, a chemical compound, and a form of carbon dioxide, acts as a buffer (base) in the body, regulating pH levels. It plays a vital role in various physiological processes, including digestion and kidney function.

This test helps diagnose and monitor conditions such as acidosis (build-up of acid in the body fluids) or alkalosis (loss of acid from the body fluids) guiding appropriate medical interventions for optimal physiological function. 

This test is also known as Carbon dioxide test, CO2 test, Total CO2, Bicarb, HCO3

Signs and symptoms of acid-base imbalance

Accelerated heartbeat (tachycardia)

Accelerated heartbeat (tachycardia)

Confusion or dizziness

Confusion or dizziness

Feeling very tired (fatigue)

Feeling very tired (fatigue)

Loss of appetite

Loss of appetite

Headache

Headache

Rapid breathing or long, deep breathing

Rapid breathing or long, deep breathing

Nausea and vomiting

Nausea and vomiting

Breath that smells sweet or fruity

Breath that smells sweet or fruity

What is a Bicarbonate, Serum test used for?

A bicarbonate, serum test is performed

As a part of routine health check-up in individuals with kidney disease, liver failure, other conditions related to metabolism

As a part of routine health check-up in individuals with kidney disease, liver failure, other conditions related to metabolism

To confirm acid-base imbalance in individuals exhibiting symptoms

To confirm acid-base imbalance in individuals exhibiting symptoms

To monitor the effectiveness of treatments and interventions aimed at managing electrolyte imbalance

To monitor the effectiveness of treatments and interventions aimed at managing electrolyte imbalance

Test preparation

Bicarbonate, serum test does not require any special preparation. Make sure your doctor is aware of what prescription drugs, over-the-counter medicines, or dietary supplements you are taking before undergoing the test

Interpretation of the Test Results

The units of measurement for the results are milliequivalents per liter (mEq/L)  

 Normal bicarbonate levels: 22 to 29 mEq/L 

Deviations from the normal levels indicate:

·       A high bicarbonate level usually indicates metabolic alkalosis (a condition that causes an increase in the pH levels in the body). This condition can be attributed to various causes including vomiting, dehydration, anorexia, and chronic obstructive pulmonary disease.

A low bicarbonate level usually indicates metabolic acidosis (a condition that causes a decrease in the pH levels in the body). This condition can be attributed to various causes including diarrhoea, kidney disease, and liver failure.

FAQs

How is the sample collected for a bicarbonate, serum test?

A healthcare professional will take a small amount of blood sample from a vein in your arm, using a small needle, which is collected into a test tube or vial.

What are the risks associated with the bicarbonate, serum test?

There are no associated risks with bicarbonate, serum test. During a blood test, one may experience minor pain or bruising where the needle was inserted

What is the turnaround time (TAT) for bicarbonate, serum test?

The bicarbonate, serum test results are usually available on the same day after sample collection

What might affect bicarbonate, serum test results?

Several factors can influence bicarbonate, serum test results. These include respiratory or metabolic disorders, kidney dysfunction, medications such as thiazide diuretics. It is crucial to consult your healthcare provider and follow specific instructions before undergoing the test

Why does a low serum bicarbonate increase the risk of kidney failure?

Low serum bicarbonate levels can indicate metabolic acidosis, linked to kidney disease progression. In renal dysfunction, the kidneys struggle to excrete acids and regulate bicarbonate. Prolonged acidosis contributes to inflammation, fibrosis, and impaired kidney function. Monitoring and managing bicarbonate levels are vital in preventing further renal damage

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