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Free T3 (FT3) Test

Free T3 (FT3)

T3 (Triiodothyronine) is one of the major hormones secreted by the thyroid glands (a small, butterfly-shaped gland situated in the lower front part of the neck). The T3 hormone comes in two different forms: bound and free. A bound T3 is attached to the protein, whereas a free T3 has no protein.

The free T3 test measures the amount of free T3 levels in the blood. If the levels of T3 are abnormal, it indicates a sign of thyroid disease.

This test is also known as Free triiodothyronine, FT3.

T3 plays a vital role in body’s metabolic rate, heart and digestive functions, muscle control, brain development and function, and maintenance of bones.

What is FT3 test used for?

This test is indicated if you experience the following signs and symptoms.

Anxiety

Anxiety

Weight loss

Weight loss

Tremors

Tremors

Increased heart rate

Increased heart rate

Bulging of the eyes

Bulging of the eyes

Insomnia (trouble sleeping)

Insomnia (trouble sleeping)

Fatigue

Fatigue

Low tolerance for heat

Low tolerance for heat

More frequent bowel movements

More frequent bowel movements

Who should get tested?

This test is indicated if you, Are older than 40 years of age

This test is indicated if you, Are older than 40 years of age

Have a thyroid problem

Have a thyroid problem

Have a family history of thyroid diseases

Have a family history of thyroid diseases

Have type 1 diabetes

Have type 1 diabetes

Have pernicious anaemia

Have pernicious anaemia

Have primary adrenal insufficiency

Have primary adrenal insufficiency

Consume lots of iodine-rich foods

Consume lots of iodine-rich foods

Take medicines that contain iodine

Take medicines that contain iodine

Have had recently been pregnant or had a baby

Have had recently been pregnant or had a baby

Test preparation:

You don’t need any special preparations to take the free T3 test. It is a simple blood test that involves the collection of your blood sample by inserting a needle in the vein in your arm. After sufficient blood is collected, the needle is taken out, and a cotton ball or piece of gauze is held at the site of needle insertion to stop the bleeding.

The whole procedure usually takes less than a few minutes.

Please tell your doctor if you are taking any medicines such as thyroid medicines, multivitamins, corticosteroids, etc., before undergoing this test, as certain medications interfere with the accuracy of the test results

Interpretation of results

The normal ranges for healthy individuals as per their age are as shown in the below table.

Age group

Normal ranges – picograms per millilitre (pg/mL)

Infants up to 3 days old

1.4-5.4

Infants up to 4 to 30 days old

2.0-5.2

Babies 1 month to 1-year-old

1.5-6.4

Children 1 to 6 years old

2.0-6.0

Children 1 to 7 years old

2.7-5.2

Children 12 to 17 years old

2.3-5.0

Adults 18 to 99 years old

2.3-4.1

 

Deviations from the normal ranges:

Any deviations from the normal ranges may indicate,

·       Higher levels of T3 than normal may be a sign of overactive thyroid glands (Graves’ disease), toxic nodular goitre, taking thyroid medicines or other supplements, liver diseases, and T3 thyrotoxicosis (rare).

·       T3 levels are also elevated during pregnancy, most commonly in women who experience morning sickness during or near the end of their first trimester, or when using birth control pills or estrogen.

·       Lower levels of T3 than usual may be a sign of severe short-term or long-term illnesses, starvation, an underactive thyroid gland, or thyroiditis (inflammation of the thyroid gland).

FAQs

What is the turnaround time (TAT) for the free T3 test?

The test results of the free T3 test are usually available within 1-2 working days after the sample collection. At times, it might take a little longer than usual

Are there any risks to the free T3 test if I take it during pregnancy?

No. There are absolutely no major associated risks with a free T3 test for either the mother or the baby. It is a simple blood test that involves blood collection from a vein in your arm. However, all blood tests have negligible risks associated with them, such as feeling a slight sting or bruise at the site of sample collection, which usually resolves within a few minutes or hours

What are the normal ranges for free T3 during pregnancy?

The normal levels of free T3 in healthy pregnant women are as shown below:

Pregnancy trimesters

1st trimester

2nd trimester

3rd trimester

Free T3 normal levels

(pg/mL)

2.9-31

2.7-33.4

2.4-36.1

 

Is it necessary to take a free T3 test during pregnancy?

It is common to have thyroid changes during pregnancy. These changes are usually very common, and most women don’t need to test for free T3. Nevertheless, your healthcare provider may suggest you undergo a free T3 test if you have:

·       Symptoms of thyroid disease such as weight loss or gain, anxiety, tremors, sweating, etc.

·       A history of thyroid disease.

·       An autoimmune disease such as Graves’ disease or Hashimoto’s thyroiditis, etc.

·       A family history of thyroid disease.

Are there any limitations to the free T3 test?

A few limitations of the free T3 test may include the following:

·       Free T3 test results are not always reliable for detecting thyroid disease. Additional testing may be required to confirm the diagnosis of thyroid disease.

·       External factors such as diet, certain illnesses such as diabetes, stress, and insufficient sleep for an extended period of time may also have an impact on test results.

Some medications, such as thyroid medications, multivitamins, corticosteroids, birth control pills, female hormones such as estrogen, male hormones such as androgens, etc., may also interfere with the results of the free T3 test

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