
Testosterone (Free, Total) Serum Test
Testosterone (Free, Total) Serum Test
Testosterone is a vital hormone in the human body, playing key roles in the development of male reproductive tissues, muscle mass, bone density, and overall well-being. While testosterone is primarily recognized as a male hormone, it is also present in smaller amounts in females and contributes to functions such as maintaining libido and energy levels. A testosterone (free, total) serum test measures the levels of both free and bound testosterone in the blood, providing valuable insights into various health conditions.
What is the Testosterone (Free, Total) Serum Test Used For?
This test is a critical diagnostic tool for evaluating testosterone levels in the body. It is often used to diagnose and monitor:
·        Hypogonadism: A condition characterized by low testosterone levels leading to reduced sexual function, energy, and mood changes.
·        Infertility: Identifying hormonal imbalances that may affect sperm production.
·        Polycystic Ovary Syndrome (PCOS): In females, this test helps assess excess testosterone production, which can contribute to symptoms such as irregular periods and excessive hair growth.
·        Delayed or Early Puberty: Evaluating abnormal testosterone levels in children or adolescents to determine the cause of developmental delays or premature puberty.
Monitoring Hormone Replacement Therapy: Assessing the effectiveness of testosterone therapy in individuals undergoing treatment for low testosterone levels.
Symptoms of Testosterone Imbalances
A testosterone (free, total) serum test may be recommended if you experience symptoms of hormonal imbalance. Common signs include: • Low Testosterone Levels

Reduced libido or erectile dysfunction

Fatigue and lack of energy

Loss of muscle mass and increased body fat

Mood changes, including depression or irritability

Difficulty concentrating or memory problems
High Testosterone Levels

Excessive hair growth or acne (especially in females)

Deepening of the voice in females

Increased aggression or irritability

Menstrual irregularities in females

Enlargement of breast tissue (gynecomastia) in males
Preparation for the Test
To ensure accurate results, follow these preparation guidelines before the testosterone (free, total) serum test:
1.    Timing of the test: Testosterone levels fluctuate throughout the day, so the test is usually performed in the morning when levels are at their peak.
2.   Fasting: Some healthcare providers may recommend fasting for a few hours before the test. Confirm with your doctor if this is necessary.
3.   Medication disclosure: Inform your healthcare provider about any medications, supplements, or treatments you are taking, as certain drugs can influence testosterone levels.
Interpretation of Results
The results of the testosterone (free, total) serum test are measured in nanograms per deciliter (ng/dL). Normal ranges may vary slightly between laboratories but typically include:
Total Testosterone:
·        Adult males: 300-1,000 ng/dL
·        Adult females: 15-70 ng/dL
Free Testosterone:
·        Adult males: 5-25 ng/dL
·        Adult females: 0.5-5 ng/dL
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Abnormal Results:
·        Low testosterone levels may indicate conditions such as hypogonadism, chronic illness, or pituitary gland dysfunction. In females, it may be associated with decreased libido and bone density issues.
·        High testosterone levels can be a sign of androgen-secreting tumors, PCOS in females, or anabolic steroid use.
It is essential to discuss your results with a healthcare provider, who can interpret them in the context of your overall health and medical history.
FAQs
What is the difference between free and total testosterone?
Total testosterone includes all testosterone in the blood, both bound to proteins (such as SHBG) and free. Free testosterone refers to the unbound form that is biologically active and available for use by the body.
Why is the test typically done in the morning?
Testosterone levels are highest in the morning and gradually decline throughout the day. Testing in the morning ensures more accurate and consistent results.
Can females have their testosterone levels checked?
Yes, testosterone testing is crucial for females experiencing symptoms such as irregular periods, excessive hair growth, or infertility.
What factors can affect testosterone levels?
Age, obesity, certain medications, stress, and underlying medical conditions like diabetes or thyroid disorders can influence testosterone levels.
How long does it take to get test results?
Results are typically available within 1-3 business days, depending on the laboratory.